A crash involving a tractor-trailer and a box truck that occurred near the Domestic Trades Entrance had police close the I-278 westbound exit ramp from Rt. 1&9 southbound.
The crash happened shortly before noon when the vehicles collided and caused the box truck to overturn according to reports.
Police detoured traffic on the highway for about two hours as hazmat crews cleaned a fluid spill then a towing company uprighted the truck.
There were non-fatal injuries reported.
Police are investigating the cause of the crash.