According to State Police, the crash occurred Sunday evening at 8:52 p.m. on I-80 westbound in Paterson.
State Police said preliminary information indicates that in the area of milepost 58.2, an Infiniti sedan ran off the right side of the road, overturned, struck several trees, then traveled down an embankment causing both passengers to eject from the car.
According to NJ State Police officials, the driver and one of the passengers sustained serious injuries and were transported to St. Joseph's Medical Center in Paterson.
The other passenger sustained fatal injuries and was pronounced dead at the scene.
The cause of the crash remains under investigation.